How are Genetically Encoded Reporters Integrated into the Genome?
The integration of genetically encoded reporters into the genome can be achieved through various methods:
1. Transfection: This involves introducing reporter genes into cells using chemical or physical means. 2. Viral Vectors: Viruses engineered to carry reporter genes can infect cells and integrate the gene into the host genome. 3. CRISPR/Cas9: This advanced technique allows for precise editing of the genome to insert reporter genes at specific locations.