How are Fibroblast Foci Identified Histologically?
In histological examinations, fibroblast foci are identified using special staining techniques. Hematoxylin and eosin (H&E) staining is commonly used to visualize tissue architecture and cell morphology. However, specific stains like Masson's trichrome or immunohistochemical markers such as vimentin and α-SMA (alpha-smooth muscle actin) can help differentiate fibroblasts from other cell types and highlight extracellular matrix components.