What is the Role of Fibroblasts in Fibroblast Foci?
Fibroblasts within fibroblast foci are not just passive structural cells; they are metabolically active and play a crucial role in the fibrotic process. They secrete collagen and other extracellular matrix proteins, which accumulate and form scar tissue. These fibroblasts can also differentiate into myofibroblasts, which have contractile properties and contribute to tissue contraction and stiffness.
