What is Nodular Lymphocyte Predominant Hodgkin Lymphoma?
Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL) is a rare subtype of Hodgkin Lymphoma that accounts for approximately 5% of all Hodgkin Lymphoma cases. Unlike classical Hodgkin Lymphoma, NLPHL is characterized by the presence of large, atypical lymphocytic and histiocytic (L&H) cells, often referred to as "popcorn cells" due to their distinctive appearance.