What Are the Challenges in Studying Serotonin Receptors?
One of the main challenges in studying serotonin receptors is their diverse distribution and the complexity of their signaling pathways. Different subtypes can have opposing effects, making it difficult to predict the overall outcome of receptor activation or inhibition. Additionally, the presence of multiple subtypes in the same tissue complicates the interpretation of experimental results. Advanced techniques such as single-cell RNA sequencing and high-resolution imaging are helping to overcome these challenges.
