How are Cell Cycle Inhibitors Studied in Histology?
Histological techniques such as immunohistochemistry (IHC) are employed to study the expression of cell cycle inhibitors in tissues. IHC involves staining tissues with antibodies that specifically bind to inhibitors like p21, p27, and p53, allowing for visualization under a microscope. This helps in determining the distribution and intensity of these proteins within tissue sections, providing insights into the cell cycle status of the cells.
