In histology, the expression of Bcl-2 family proteins can be evaluated using techniques such as immunohistochemistry (IHC), Western blotting, and immunofluorescence. IHC is particularly useful for visualizing the localization and relative abundance of these proteins in tissue sections. Antibodies specific to Bcl-2, Bax, Bak, and other family members are used to stain tissue samples, allowing pathologists to assess the role of these proteins in various diseases.
