Management of balanced rearrangements depends on their clinical implications. Genetic counseling is crucial for affected individuals and families to understand the risks and options. In cases where fertility is affected, assisted reproductive technologies (ART) and preimplantation genetic diagnosis (PGD) may be considered.
For conditions like CML associated with specific rearrangements, targeted therapies such as tyrosine kinase inhibitors are effective in managing the disease by inhibiting the aberrant protein produced due to the rearrangement.
