In histology and cytogenetics, balanced rearrangements are typically detected using several laboratory techniques:
Karyotyping: This traditional method allows visualization of the entire chromosome set under a microscope, helping to identify large-scale rearrangements. Fluorescence In Situ Hybridization (FISH): FISH uses fluorescent probes to detect specific DNA sequences on chromosomes, useful for identifying specific rearrangements. Next-Generation Sequencing (NGS): This advanced technique provides detailed information about genomic rearrangements at the nucleotide level.
