In some cases, cytoskeletal breakdown can be reversed if the underlying cause is addressed. For example, cells can recover their cytoskeletal integrity after the removal of stressors or toxins. However, in the context of apoptosis or necrosis, the breakdown is irreversible and leads to cell death. Therapeutic interventions targeting cytoskeletal proteins or their regulatory pathways are being explored for conditions associated with abnormal cytoskeletal dynamics.
