Histological markers for drug toxicity vary depending on the affected organ and the type of drug. In the kidneys, for example, nephrotoxic drugs like certain antibiotics and chemotherapy agents may cause tubular necrosis, interstitial inflammation, and fibrosis. In the lungs, drugs like amiodarone can cause pulmonary fibrosis, observable as thickened alveolar walls and increased connective tissue. Identifying these markers is essential for diagnosing drug-induced tissue damage.
