Can Medications Cause Histological Changes in the Liver?
Yes, many medications can induce histological changes in the liver. Drugs like acetaminophen, certain antibiotics, and statins are known to cause hepatotoxicity. Histological examinations of liver biopsies from patients with drug-induced liver injury may show signs of hepatocyte necrosis, steatosis (fat accumulation), inflammation, and fibrosis. Recognizing these patterns is crucial for diagnosing and managing drug-induced liver diseases.