Are There Any Histopathological Markers of Zinc Toxicity?
Excess zinc can also be detrimental, leading to histopathological changes such as cellular apoptosis and necrosis. Toxic levels of zinc can disrupt cellular homeostasis, leading to oxidative stress and damage to cellular organelles. In the liver, for instance, zinc toxicity can result in hepatocyte damage and inflammation, characterized by the presence of necrotic cells and inflammatory infiltrates.