Are There Any Clinical Implications of Fucosylated Glycoconjugates?
Yes, alterations in the expression of fucosylated glycoconjugates are associated with various diseases. For instance, changes in their distribution and levels are observed in cancer, where they can influence tumor progression and metastasis. In inflammatory diseases, abnormal fucosylation patterns can affect immune responses and tissue inflammation. Moreover, in genetic disorders like congenital disorders of glycosylation, defects in fucosylation can lead to multiple systemic abnormalities.
