What is the Role of GPCRs in Cellular Communication?
GPCRs mediate a wide array of physiological processes by transmitting signals from the extracellular environment to the cell's interior. When a ligand binds to a GPCR, it induces a conformational change in the receptor, which activates the associated G protein. This activated G protein then modulates various intracellular signaling pathways, influencing cellular responses such as gene expression, enzyme activity, and ion channel function.
