What are the Implications of Parkin Dysfunction in Neurodegenerative Diseases?
Dysfunctional parkin has broad implications in neurodegenerative diseases beyond Parkinson's disease. It has been implicated in disorders such as Alzheimer's disease and amyotrophic lateral sclerosis (ALS). The loss of parkin's protective role in these diseases highlights its importance in maintaining neuronal health and preventing neurodegeneration.