The importance of transpeptidase extends beyond its biological function. In clinical settings, the inhibition of transpeptidase by antibiotics is a key strategy in combating bacterial infections. By binding to the active site of transpeptidase, β-lactam antibiotics prevent the enzyme from forming cross-links, thereby weakening the cell wall and leading to bacterial death. Understanding transpeptidase activity helps histologists and pathologists diagnose infections and develop effective treatment plans.
