Why are Knockout and Knockdown Experiments Important in Histology?
Histology focuses on the microscopic structure of tissues, and understanding how genes regulate these structures is crucial. Knockout and knockdown experiments help elucidate the roles of specific genes in tissue development, differentiation, and pathology. For example, knocking out a gene involved in cell adhesion can reveal its role in maintaining tissue architecture. Similarly, knocking down a gene implicated in cell signaling can help understand its impact on tissue responses to external stimuli.