Why are Double Strand DNA Breaks Significant in Histology?
In histology, the study of the microscopic structure of tissues, understanding DSBs is crucial because they can lead to apoptosis or uncontrolled cell growth if not properly repaired. This can result in tissue degeneration or the formation of tumors. Additionally, DSBs play a critical role in processes such as meiosis and immunoglobulin class switching, which are essential for reproductive and immune system functions, respectively.
