Several types of 3D culture systems are used, each with its unique properties and applications:
- Scaffold-Based Systems: These use natural or synthetic materials to provide a framework for cell growth. Common materials include collagen, gelatin, and synthetic polymers. - Hydrogel-Based Systems: Hydrogels are water-swollen networks of polymers that provide a highly hydrated environment, ideal for cell growth and differentiation. - Spheroid and Organoid Cultures: Spheroids are simple 3D structures, while organoids are more complex and can replicate the architecture and functionality of actual organs. - Bioreactors: These are dynamic systems that provide mechanical and biochemical cues to cells, enhancing the formation of tissue-like structures.
