What Techniques are Used to Study Protein-DNA Interactions in Histology?
Several techniques are employed to study protein-DNA interactions in Histology:
Chromatin Immunoprecipitation (ChIP): This technique allows for the identification of specific DNA sequences bound by proteins in vivo. Electrophoretic Mobility Shift Assay (EMSA): This method is used to detect protein-DNA interactions by observing the mobility of DNA-protein complexes in a gel. DNase I Footprinting: This technique identifies protein-binding sites on DNA by detecting regions protected from DNase I digestion.
