What Techniques are Used to Study Protein Complexes?
Beyond visualization, several techniques are used to study protein complexes in histology. Co-immunoprecipitation (Co-IP) is a method to identify protein-protein interactions by using specific antibodies to isolate a protein complex from tissue lysates. Mass spectrometry can then be used to analyze the complex's components. Additionally, cryo-electron microscopy allows for high-resolution structural analysis of protein complexes.
