What Techniques are Used to Study Neoplastic Tissues?

Several histological techniques are employed to study neoplastic tissues:
- Hematoxylin and Eosin (H&E) staining: This is the most common method used to evaluate the general architecture and cell morphology of tissues.
- Immunohistochemistry (IHC): This technique uses antibodies to detect specific antigens in cells, helping to identify the tissue origin of undifferentiated tumors and to distinguish between benign and malignant lesions.
- Special stains: Various stains like PAS, Masson's trichrome, and silver stains are used to highlight specific tissue components, aiding in the diagnosis of certain neoplasms.
- Molecular techniques: Techniques such as fluorescence in situ hybridization (FISH) and polymerase chain reaction (PCR) are used to detect genetic abnormalities associated with neoplasms.