What Techniques are Used to Study Genetic Conditions in Histology?
Several techniques are employed to study genetic conditions in histology:
- [Histochemical Staining](): This technique uses specific stains to identify abnormalities in tissue structure and composition. For example, Masson's trichrome stain can highlight fibrosis in tissues affected by genetic conditions. - [Immunohistochemistry (IHC)](): IHC uses antibodies to detect specific proteins within tissues. It is useful in identifying the presence or absence of proteins affected by genetic mutations. - [In Situ Hybridization (ISH)](): ISH allows for the detection of specific DNA or RNA sequences within tissues, providing insights into gene expression patterns affected by genetic disorders. - [Electron Microscopy](): This technique provides high-resolution images of tissue ultrastructure, enabling the observation of cellular abnormalities caused by genetic mutations.
