What Staining Techniques are Used to Identify Lipid Storage Diseases?
Histological examination of tissues suspected of lipid storage diseases often involves specific staining techniques. Oil Red O and Sudan Black are commonly used lipid-specific stains that highlight lipid accumulations within cells. Additionally, Periodic acid-Schiff (PAS) staining can be useful for identifying glycolipid accumulations. Electron microscopy may also be employed to observe the ultrastructural details of lipid-laden organelles.