brain tumors

What Role Does Immunohistochemistry Play in Brain Tumor Diagnosis?

Immunohistochemistry (IHC) is crucial for the diagnosis and classification of brain tumors. By using antibodies that target specific antigens, IHC can help identify the cell of origin and determine the expression of molecular markers. For example:
GFAP (Glial Fibrillary Acidic Protein): Used to identify astrocytic tumors.
Synaptophysin and Chromogranin: Markers for neuronal and neuroendocrine differentiation.
EMA (Epithelial Membrane Antigen): Often positive in meningiomas.

Frequently asked queries:

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