assessing connective tissue disorders

What Role Do Immunohistochemistry and Molecular Techniques Play?

Immunohistochemistry (IHC) and molecular techniques have significantly enhanced the diagnostic capabilities in histology. IHC uses antibodies to detect specific antigens in tissues, providing more precise information about the presence and distribution of proteins associated with CTDs. Molecular techniques, such as polymerase chain reaction (PCR) and next-generation sequencing (NGS), can identify genetic mutations and other molecular abnormalities, offering insights into the underlying causes of CTDs.

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