Several methods are employed for cell tracking in histology, each with its unique advantages and limitations:
Fluorescent Labeling: Cells are tagged with fluorescent molecules that emit light upon excitation. This allows for real-time visualization using fluorescence microscopy. Genetic Labeling: Genetic markers such as Green Fluorescent Protein (GFP) are introduced into the cell's DNA, making them express a fluorescent protein. Nanoparticles: Cells are labeled with nanoparticles that can be detected using specific imaging techniques like MRI or CT scans. Bioluminescence Imaging: This method involves the introduction of bioluminescent proteins into cells, which emit light through a chemical reaction.