TNFR2, or Tumor Necrosis Factor Receptor 2, is a receptor that binds to the cytokine Tumor Necrosis Factor (TNF). It plays a significant role in the regulation of immune responses and inflammation. TNFR2 is part of the TNF receptor superfamily and is encoded by the TNFRSF1B gene. The receptor is expressed on a variety of cell types, including immune cells, endothelial cells, and some subsets of neurons.