What is the significance of the Loop of Henle in renal histology?
The Loop of Henle extends into the renal medulla and is crucial for the concentration of urine. It consists of descending and ascending limbs with thin and thick segments. The thin descending limb is permeable to water but not to ions, while the thick ascending limb actively transports ions but is impermeable to water. These differential properties create a countercurrent multiplier system essential for urine concentration.
