What histological changes occur in renal diseases?
Various renal diseases induce characteristic histological changes: - Glomerulonephritis: Inflammation of the glomeruli, often showing increased cellularity and basement membrane thickening. - Diabetic Nephropathy: Thickening of the glomerular basement membrane and mesangial expansion. - Acute Tubular Necrosis: Damage to the tubular epithelial cells, leading to loss of brush border and cellular necrosis. - Polycystic Kidney Disease: Formation of numerous cysts in the renal cortex and medulla, displacing normal tissue.
