What is the Role of Mitochondria in Calcium Homeostasis?
Mitochondria help regulate intracellular calcium levels. They can uptake and release calcium ions (Ca2+), thereby participating in calcium signaling pathways that affect various cellular processes, including muscle contraction, neurotransmitter release, and enzyme activity. Dysregulation of mitochondrial calcium handling can lead to cell death and is implicated in various diseases, including neurodegenerative disorders.