What is the Role of Kinetochore Microtubules in Chromosome Segregation?
During anaphase, kinetochore microtubules shorten, pulling the sister chromatids apart toward opposite spindle poles. This process is driven by motor proteins such as dynein and kinesin, which move along the microtubules, coupled with the depolymerization of tubulin at the kinetochore end. The accurate segregation of chromosomes is essential to prevent aneuploidy and ensure the genetic stability of daughter cells.
