What is the Role of IL-13 in Disease Pathogenesis?
IL-13 is involved in the pathogenesis of several diseases, particularly those with an inflammatory or allergic component. Key examples include:
Asthma: IL-13 promotes airway inflammation, mucus production, and bronchoconstriction. Atopic Dermatitis: IL-13 contributes to the inflammatory response and skin barrier dysfunction. Pulmonary Fibrosis: IL-13 induces fibroblast proliferation and collagen deposition, leading to lung tissue scarring.
