IL-13 can induce several histological changes, including:
Epithelial Cell Hyperplasia: Increased number of epithelial cells, commonly observed in the respiratory and gastrointestinal tracts. Fibrosis: Excessive deposition of extracellular matrix proteins, leading to tissue stiffening and scarring. Goblet Cell Metaplasia: Transformation of epithelial cells into goblet cells, which produce mucus. Increased Collagen Production: Enhanced synthesis of collagen by fibroblasts, contributing to fibrosis.
