What is the Impact of CNVs on Histological Features?
CNVs can significantly impact histological features. For example, in cancer, CNVs may lead to the overexpression or deletion of oncogenes and tumor suppressor genes, respectively. This can result in abnormal cell morphology, increased proliferation, and resistance to apoptosis, which are observable under the microscope. In neurodevelopmental disorders, CNVs can affect brain development and structure, influencing the histological appearance of brain tissues.
