What is the Histological Significance of S100 Proteins?
In histology, S100 proteins are often used as biomarkers for specific cell types and pathological conditions. For instance, S100B is a common marker for glial cells in the central nervous system, while S100A4 is associated with metastatic potential in cancer cells. Their expression patterns can help in diagnosing and understanding various diseases, including melanoma and neurodegenerative disorders.