What is the Functional Significance of GABA in the Nervous System?
GABA plays a critical role in maintaining the balance between neuronal excitation and inhibition. It acts on GABAA and GABAB receptors to mediate fast inhibitory synaptic transmission and slow inhibitory signals, respectively. Dysregulation of GABAergic signaling is implicated in various neurological disorders, including epilepsy, anxiety, and schizophrenia.