What is the Functional Significance of Each Layer?
Each cortical layer has distinct functions and connectivity:
- Layer I: Mainly involved in receiving synaptic inputs from other cortical areas and modulating the activity of deeper layers. - Layer II and III: Participate in local processing and inter-cortical communication. - Layer IV: Receives thalamic inputs and is essential in sensory processing. - Layer V: Sends outputs to subcortical structures, including the spinal cord; crucial for motor control. - Layer VI: Provides feedback to the thalamus and other cortical areas, helping in modulating sensory information.