The primary functions of intestinal crypts include:
Cell Regeneration: The crypts house stem cells that continuously divide and differentiate into various types of epithelial cells, facilitating the renewal of the intestinal lining every few days. Secretion: Goblet cells within the crypts secrete mucus, which helps in the lubrication and protection of the intestinal surface. Paneth cells secrete antimicrobial peptides that contribute to the innate immune defense. Absorption: Although absorption primarily occurs in the villi, some absorption of nutrients and water can occur in the crypts as well. Hormonal Regulation: Enteroendocrine cells release hormones that regulate digestive secretions and motility.
