langhans giant cells

What is the Difference Between Langhans Giant Cells and Foreign Body Giant Cells?

While both Langhans giant cells and foreign body giant cells are types of multinucleated giant cells, they differ in their nuclear arrangement and origin. Langhans giant cells have nuclei arranged in a horseshoe or circular pattern, whereas foreign body giant cells have nuclei dispersed throughout the cytoplasm. The latter typically form in response to the presence of foreign materials such as sutures, splinters, or other indigestible substances.

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