Abnormalities in fibrillarin expression or function can have significant clinical implications. For instance, dysregulation of fibrillarin has been linked to certain types of cancer. Additionally, mutations in the gene encoding fibrillarin can lead to disorders such as Treacher Collins syndrome, a condition characterized by craniofacial deformities. Therefore, understanding fibrillarin's role in normal cellular processes and disease states is crucial for developing potential therapeutic strategies.
