In histology, fibrillarin can be studied using various techniques. Immunohistochemistry (IHC) and immunofluorescence (IF) are common methods used to visualize fibrillarin within cells. These techniques involve the use of antibodies specific to fibrillarin, which are tagged with fluorescent dyes or enzymes that produce a colorimetric reaction. These methods allow researchers to observe the localization and abundance of fibrillarin in different cell types and tissues.