What is the Clinical Significance of Balloon Cells?
The presence of balloon cells in a tissue sample can indicate underlying pathological conditions. For instance, in the liver, balloon cells are a hallmark of liver injury and can be indicative of conditions such as alcoholic hepatitis, non-alcoholic steatohepatitis (NASH), or viral hepatitis. In the skin, balloon cells can be seen in conditions like herpes simplex virus (HSV) infections, where keratinocytes become swollen and vacuolated.