Decorin's role in maintaining ECM integrity and modulating cell signaling makes it relevant in various clinical contexts. Some examples include:
Wound Healing: Due to its involvement in collagen fibrillogenesis and modulation of growth factors, decorin is a potential therapeutic target for enhancing wound repair and reducing scar formation. Fibrotic Diseases: Abnormal decorin expression is associated with fibrosis in organs such as the liver, lungs, and kidneys. Therapies targeting decorin could help manage fibrotic conditions. Cancer: Given its anti-tumor properties, decorin is being explored as a potential therapeutic agent in cancer treatment. It could be used to inhibit tumor growth and metastasis.
