cohesin

What is the Clinical Relevance of Cohesin?

Given its pivotal role in maintaining chromosome integrity, cohesin is a significant target in cancer research. Abnormal cohesin function is linked to various cancers, including breast, colorectal, and hematological malignancies. Understanding cohesin's mechanisms can lead to novel therapeutic strategies. For example, targeting cohesin pathways might enhance the efficacy of existing treatments like chemotherapy and radiotherapy by increasing cancer cells' sensitivity to DNA damage.

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