What is Proliferating Cell Nuclear Antigen (PCNA)?
Proliferating Cell Nuclear Antigen (PCNA) is a protein that acts as a processivity factor for DNA polymerase δ in eukaryotic cells. It is essential for DNA replication and is involved in various stages of the cell cycle. PCNA forms a trimeric ring that encircles DNA, serving as a sliding clamp to increase the polymerase's processivity during DNA synthesis.
