Presenilin refers to a family of related proteins that play a crucial role in the regulation of various cellular processes. These proteins are integral membrane proteins and are chiefly known for their involvement in the pathogenesis of Alzheimer's Disease (AD). The two main types are Presenilin-1 (PS1) and Presenilin-2 (PS2), which are coded by the PSEN1 and PSEN2 genes respectively.
