In the context of histology, the term mobile fraction refers to the proportion of a specific molecule or protein within a cell that is free to move within a particular cellular compartment or structure. This concept is crucial in understanding the dynamics of cellular cytoskeleton, membrane-bound proteins, and intracellular signaling molecules. The mobile fraction is typically measured using fluorescence recovery after photobleaching (FRAP), a technique that allows researchers to observe the movement and recovery of fluorescently tagged molecules after a specific region has been photobleached.
