What is Interleukin 1 Receptor Antagonist (IL-1Ra)?
Interleukin 1 Receptor Antagonist (IL-1Ra) is a naturally occurring protein that inhibits the activity of interleukin 1 (IL-1) by binding to its receptors without eliciting a response. It is an important component of the immune system's regulatory mechanisms, balancing the pro-inflammatory effects of IL-1. IL-1Ra is produced by various cell types, including monocytes, macrophages, and endothelial cells, and plays a crucial role in modulating inflammation and immune responses.